Pnm-26: The Association Between Maternal Body Mass Index During First Trimester of Pregnancy with Preeclampsia

Background: Preeclampsia is the most important problems in pregnancy that irreparable complications for mother and fetus has. Maternal body mass index in the first trimester of pregnancy and weight gain during pregnancy is important in pregnancy outcome. This study to determine the association BMI first trimester mothers with preeclampsia have been done Materials and Methods: In this prospective cohort study, 300 singleton pregnant women in their 1 to 13 gestational weeks presented at prenatal care clinic of Milad Hospital, Tehran during 2009-2010 were recruited in the study using convenience sampling. Exclusion criteria were of age less than 18 and more than 35 years, multiple pregnancy, history of underlying problems and adverse pregnancy outcomes. A questionnaire was used as the data collection tool filled out through interviews with the mothers; mothers were weighted and their height was measured using the same balance and meter. Gestational age was determined according to the date of the last menstrual period. The subjects were followed up to delivery time in order to observe preeclampsia, if occurred. SPSS statistical software version 18 was applied and parametric and non-parametric tests were used for statistical analysis Results: The mean maternal age was 27.3 ± 3.8 years and the mean weight gain during pregnancy was 12.5 ± 4.1. The incidence of preeclampsia study 7.8 percent. Mean weight gain during pregnancy, preeclampsia in 13.5 ± 5.21kg. The highest percentage of subjects with preeclampsia, body mass index 29 or more in the first trimester had. Risk of giving preeclampsia in women with a high body mass index(BMI 26 or more) was 2.19 times more than women with normal body mass index (OR = 2.19, 95%CI = 0.97-4.9). The findings of this study show that there are significant differences between maternal body mass index in the first trimester of pregnancy and preeclampsia (p=0.008). Conclusion: It seems that maternal body mass index during first trimester of pregnancy and excessive weight gain in pregnancy can be a predictive factor for developing preeclampsia and its helpful in recognizing mothers at risk of preeclampsia.